The Biographical Directory of the United States Congress (http://bioguide.congress.gov) gives the following outline of Prescott Bush's life:
BUSH, Prescott Sheldon, (father of George Herbert Walker Bush), a Senator from Connecticut; born in Columbus, Franklin County, Ohio, May 15, 1895; attended the Douglas School of Columbus, Ohio, and St. George’s School, Newport, R.I., 1908-1913; graduated from Yale University in 1917; enlisted in Connecticut National Guard in 1916 and served as captain of Field Artillery in American Expeditionary Forces 1917-1919; engaged in hardware business as a warehouse clerk in St. Louis, Mo.; moved to Greenwich, Conn., in 1924; engaged in banking business in New York City 1926; moderator, Greenwich Representative Town Meeting 1935-1952; trustee, Yale University; unsuccessful Republican candidate for the United States Senate in 1950; elected as a Republican to the United States Senate to fill the vacancy caused by the death of James O’Brien McMahon in 1952; reelected in 1956 and served from November 4, 1952, to January 2, 1963; was not a candidate for reelection in 1962; resumed his career in the banking and investment field; died in New York City, October 8, 1972; interment in Putnam Cemetery, Greenwich, Conn
This summary leaves out a few interesting bits:
Bush was one of the directors of, and a shareholder in, the Union Banking Corporation (UBC). On October 20, 1942, the US Alien Property Custodian seized all shares in the bank for violation of the Trading with the Enemy Act, for its ongoing support of Nazi Germany. UBC was one of a number of companies run by Bush, his father-in-law George Herbert Walker, and Roland and Averill Harriman that were involved in financing and supplying Nazi Germany. Among them was the Silesian-American Corporation, managed by Bush and Walker, which supplied coal to Germany and was seized for trading with the enemy on November 17, 1942.
Bush was also a favorite golfing partner of President Eisenhower and one of Richard Nixon's political mentors (along with Allen Dulles).