In the
Vampire: The Masquerade role-playing game,
Sanguinus is the unique
Discipline of the
Blood Brothers bloodline. The
Blood Brothers, a
vampire bloodline created as a result of experimentation by
Tzimisce fleshcrafters and
Koldunic sorcerors, with the assistance of the
Tremere antitribu, are primarily intended for physical combat, much as
Virstania's
Gargoyles were intended during the early days of
Clan Tremere. Blood Brothers work in collective packs, with a group mind directing their actions.
Blood Brother collectives use Sanguinus to coordinate their actions, share blood and thought, and at higher levels can use it to combine their very bodies to form massive, powerful war-forms. Like war ghouls, but much, much worse.