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Monomolecular blades are tools (or weapons) that have a cutting edge that is a single molecule wide. This makes them very sharp. A monomolecular blade can cut through all but the strongest of substances with almost no resistance.

Depending on the type of blade it can either stay only a few molecules thick, or it can become as thick as a normal knife.
The closest humans have come to creating monomolecular blades are special surgeon's scalpels. These are not actually monomolecular, but they come close.

see also: monofilament, monomolecular

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