Molecular Biology technique most famous for its involvement in the OJ Simpson trial. It involves amplifying a genomic DNA sample using PCR, then digesting that sample with a Restriction Enzyme. This chops the DNA into fragments which are then sorted using gel electrophoresis. The pattern produced is distinctive, with the most commonly quoted percentage of a match being 1 in 16 million. Its limitations are that the DNA sample must be from only one source, and it has relatively low accuracy when compared to DNA sequencing.

Also known as Restriction fragment length polymorphisms.