Famed Gonzo journalist Hunter S. Thompson, on the basis of personal experience with the drug, suspected that Ed Muskie was using heavy doses of ibogaine during his 1972 campaign for the Democratic nomination. Effects of heavy ibogaine use, according to Thompson, are nervousness, violent mood swings, and surreal hallucination. Speaking of an incident in Florida, in which Muskie flipped out in the back of a train, while being heckled, he says:
It is entirely possible -- given the known effects of Ibogaine -- that Muskie's brain was almost entirely paralyzed by hallucinations at the time; that he looked out at the crowd and saw gila monsters instead of people, and that his mind snapped completely when he felt something large and apparently vicious clawing at his legs.
Of course, this could have been the effect of a political campaign on a completely unstable mind...