Run is a volcanic atoll the Banda Islands, in what is now the Indonesian archipelago. In the 17th century, Run was famous and desired for its nutmeg trees. While most of the "Spice Islands" were under Dutch control, Run was claimed by Britain.
The later Dutch conquest of Run so incensed James, Duke of York that he invaded New Netherland (Manhattan) during one of the two countries' periodic wars. Negotiations resulted in the Treaty of Breda in 1667, which left the conquered territories with the conquerors--- a de facto swap of the tiny island of Run for the whole of New York.
Source: Giles Milton, Nathaniel's Nutmeg. New York: Penguin Books, 1999.