In Mage the Ascension, Entropy is the Sphere that allows one to change Destiny. As the universe is fated towards disorganization, masters of Entropy understand that it is easier to ride the tide of Fate than to go against it, and with their skill, are able to quantify probability energy (more commonly understood as Fate, Destiny, or Fortune) for their own purposes.

Apprentices in this Sphere are able to judge probabilities with an uncanny accuracy and later to alter the course of simple probabilities, while masters are able to affect complex life processes with curses or blessings as well as alter someone's worldview by pointing their thoughts along a certain path. Masters of this Sphere either tend towards a chaotic, random way of life, or a clean, orderly path manner and thought.

The Euthanatos have adopted this Sphere as their own.