I know several people who have taken pills containing illegal drugs (mostly ecstasy) by other means than the recommended oral route. They have crushed and snorted them, or inserted them into the anus or vagina.
This can be refered to as experiencing anal ecstasy.
The rectal or vaginal routes offer higher absorbtion rates than oral ingestion due to the sensitve mucous membranes, but are not as quick or intense as a smoked or injected drug.
How witches fly: If the stories about the medieval witches are to be believed, recreational suppositories have a long history. Those stories about witches flying on broomsticks are apparently based on a practice of administering flying ointment on the end of a broom handle.