DXM, in addition to
neurotoxicity issues common to all
disassociatives, has some health issues specific to its interactions with
MDMA.
Both DXM and MDMA are broken down by the same
enzyme (
CYP-2D6), and it puts an incredible load on your liver, often causing
heatstroke and/or
liver failure. More than a few E'd up
ravers have died after accidentally taking a pill they thought was MDMA, that turned out to be DXM.