A progressive degenrative disease that attacks nerve cells in the brain and spinal cord. These cells are prevented from receiving proper nourishment, and begin to atrophy. As the motor neurons that control muscle ability in the body die off, the brain begins to lose control of the muscles, until the victim is completely paralyzed. When control for vital functions is lost, the ALS sufferer dies. Most people still retain full functionality of their brain through the full scope of the disease.

www.alsa.org says the cause of ALS is not completely understood, but I seem to recall a discovery of the gene responsible for the disease in 1994 or 1995, shortly after my uncle died of ALS. ALS cannot be halted or reversed, but its progress can be slowed with the drug Rilutek. Other drugs for ALS are still in clinical trials.