ACE inhibitors
Brand/Generic Drug Names
Lotensin/ benazepril, Vasotec/enalapril, Monopril/fosinopril, Accupril/quinapril, Altace/ramipril, Capoten/captopril, Prinivil and Zestril/lisinopril, trandolapril
hypertension, congestive heart failure, diabetic nephropathy, left ventricular dysfunction after myocardial infarction, pheochromocytoma
competitively block the angiotensin I converting enzyme necessary for conversion to angiotensin II, decreasing vascular tone, lowering blood pressure, blocking release of aldosterone, increasing plasma renin activity
pregnancy
history of angioedema, impaired renal function, hyperkalemia, hyponatremia, volume depletion, allergy, cerebrovascular and coronary insufficiency
Severe hypotensive episode: alcohol, diuretics Hyperkalemia: potassium-sparing diuretics, low-salt milk, potassium supplements, potassium-containing medications/salt substitutes
dry cough, headache, nausea, diarrhea, loss of taste, weakness, dizziness, hypotension, rash, fever, joint pain, neutropenia, agranulocytosis, pancreatitis, nephritic syndrome
Assess vitals, blood and renal studies Evaluate therapeutic response: decreased blood pressure
August 06, 2002