A term which took on a new meaning during the early 90's when a "disgruntled postal worker” took an automatic fire arm to work and mowed down everyone in sight. It was later discovered through poling and other scientific studies, that being a postal worker is the second most depressing job a person can have (next to dentistry). Now when you enter the post office you see a comparatively more cheerful environment as I have noticed. The workers play the radio loud and have pictures and decorations up around their stations.

So basically, when someone is said to have "gone postal" it either figuratively means that they got very angry and most probably yelled or it literally means they opened fire with a gun on a mass of innocent people. Fun fun.