Maniac Mansion for the PC had two versions- one with blue-skin Edisons and one with flesh-tone Edisons. The NES version had only the blue-skins. The original version, by the way, was the blue-skin; this was presumably intentional as the heroes had flesh-tone skin. I always blamed it on the meteor or radiation from Dr. Fred's nuclear reactor.

Incidentally, the NES version did have a variation: something like 25,000 copies got sold before the Nintendo censors caught the hamster in the microwave trick. As a result, 25,000 lucky bastards have can microwave the hamster (that sounds dirty, but it's a story for another write-up). A later release did not allow you to microwave the hamster; everybody would say something along the lines of "that's cruel!"