A rule of thumb for predicting the solubilities of solutes in solvents.

In general, substances that have similar intermolecular forces have strong solute-solvent interactions and tend to form solutions.

Polar compounds dissolve in polar compounds and nonpolar compounds dissolve in nonpolar compunds.

Ergo:

  • Gasoline dissolves grease
  • Salts dissolve in water
  • Grease does not dissolve in water
  • Salt does not dissolve in gasoline
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