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Usually the result of eating too much spicy food (usually Cluck U's thermonuclear wings, in my case). The symptoms are liquid acidy fire in the stomach, a lingering burning sensation in the mouth, and later, hot napalm shits that would make Jesus himself beg his Dad for mercy.

In my opinion, this is the price of admission for really good spicy food. I consider it a sign that I've been eating well.

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