The difference between science and religion is in the method each uses to discuss the world. Although both rely on first principles which must be assumed, religion and science build on these using completely different criteria.

For example, a scientific theory must be refutable; there must be some hypothetical experimental or observational result which, if found, would disprove some or all of the theory. There are many other criteria that scientific theories must meet in order to follow the scientific method.

This does not mean that religion is wrong or necessarily should compete with science. These can be complementary ways of looking at the world. Religious myths are metaphors which teach us about a culture's values and ideas. The factuality of the myth has little importance.

The difference between science and religion is the difference between understanding the innards of a Swiss watch and caring that 4pm is when your Mom gets home.