Around here I have to product documents that the suits can read, and PDFLaTeX has made my job quite a bit more pleasent. To try to dump from DVI to postscript to PDF ends up with crappy looking fonts in Acrobat. My boss wouldn't let me distribute postscript files to the customers, but he seems to accept PDF's just fine.

My other option is to do my docs in Microsoft Word, clearly unacceptable.

Also, it is much easier to embed stuff like JPEG files into PDFLaTeX, but you have to convert your EPS files to PDF first, unlike normal LaTeX where you can use them directly. Use epstopdf to do this.