Delestrogen® Injection
Brand Names: Alora®; Climara®;
Delestrogen®; DepGynogen®; Depo-Estradiol®; Depogen®;
E-Cypionate®; Esclim®; Estrace®; Estrace® VR; Estraderm®; Estragyn LA 5®;
Estrasorb™; Estring®; Estro-Cyp®; Estro-L.A.®; FemPatch®; Gynodiol®; Gynogen
LA®; Innofem®; Menaval®; Noven®; Vagifem™; Valergen®; Vivelle™; Vivelle-Dot™
This medication is manufactured by Bristol-Myers Squibb Company.
Estradiol Valerate® Injections, (Delestrogen® Injections) are injections
containing an estrogen female hormone. Estrogens are essential for maintaining
normal female functions. Estrogens can help relieve symptoms of menopause
such as: hot flashes, night sweats, mood changes, and vaginal dryness and
irritation. Estrogens can also help improve female functions in women with
hormonal imbalance or problems with their ovaries. Estrogens can be given to
patients with inoperable breast cancers (in men or women) or prostate cancer.
Generic estradiol cypionate and estradiol valerate injections are available.
Your health care professional should know if you have any of the
following complications:
- allergic reaction to benzyl alcohol or chlorobutanol
- asthma
- blood vessel disease, blood clotting disorder, or suffered a stroke
- breast, cervical, endometrial or uterine cancer
- diabetes
- fibroids in the womb, or endometriosis
- heart, kidney or liver disease
- high blood lipids or cholesterol
- high blood pressure
- high level of calcium in the blood
- hysterectomy
- mental depression
- migraine
- porphyria
- tobacco smoker
- vaginal bleeding
- an unusual or allergic reaction to estrogens, other
hormones, medicines, foods, dyes, or preservatives
- pregnant or trying to get pregnant
- breast-feeding
Drugs that may interact with Delestrogen® Injections:
- some antibiotics used to treat infections
- some medications used to treat HIV (human immunodeficiency virus)
infection or AIDS
- ascorbic acid/vitamin C supplements
- barbiturates or benzodiazepines used for inducing sleep or treating
seizures (convulsions)
- bromocriptine
- carbamazepine
- cimetidine
- clofibrate
- cyclosporine
- dantrolene
- medications for diabetes
- griseofulvin
- hormones
- hydrocortisone, cortisone, or prednisolone
- imipramine or some other antidepressants
- isoniazid (INH)
- methotrexate
- mineral oil
- phenytoin
- raloxifene or tamoxifen rifabutin, rifampin, or rifapentine
- some medications for treating migraines
- theophylline
- thyroid hormones
- topiramate
- tricyclic antidepressants
- warfarin
Medication Storage
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F);
do not freeze. Throw away any unused medicine after the expiration date.
Keep out of the reach of children.
SIDE EFFECTS:
In addition to the risks listed above, the following side effects have been
reported with estrogen use: nausea and vomiting, breast tenderness or
enlargement, enlargement of benign tumors ("fibroids") of the uterus, retention
of excess fluid. This may make some conditions worsen, such as asthma,
epilepsy, migraine, heart disease, or kidney disease, or a spotty darkening of
the skin, particularly on the face
Personal Experience:
I was suffering from hot flashes, night sweats, sleeping problems and mood
swings before taking this medication. I have to go the the physician's
office once a month to have the injection administered into my hip. It has
been a life saver for me after my hysterectomy at the age of 30. All of
the problems I had before are almost non-existent now.
Source: Ebscohost Research Database. 23 Jul 2004
http://www.epnet.com/;.
Monarch Pharmaceuticals. Patient information for Delestrogen. Bristol: , 2002.