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A technique used to determine how similar two strands of single-stranded nucleic acids are to each other by putting them with a third strand (called a standard) and observing how well they can bond with each other to become double-stranded (how well they hybridize).

The information in this writeup was taken from the science dictionary at http://biotech.icmb.utexas.edu/; I oversaw the development of the dictionary. For copyright details, see the BioTech homenode.

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