Succinate

The succinate form of a chemical is often used in drugs or vitamins to enhance chemical stability without compromising bioavailability. For example, one of the main forms of Vitamin E is d-alpha-tocopheryl succinate. The succinic acid molecule is removed easily by stomach enzymes such as succinate dehydrogenase, but while present it prevents the vitamin E from being oxidized by the surrounding air.

Other drugs commonly provided in the succinate form include sumatriptan (Imitrex®) and metoprolol (Toprol®).

Suc"ci*nate (?), n. [L. succinum, sucinum, amber, from succus, sucus, juice, sap: cf. F. succinate.] Chem.

A salt of succinic acid.

 

© Webster 1913.