In some scientific experiments in, say, medicine or biology, you have a lot of control over your subjects and your independent variables--you can randomly assign subjects to certain conditions and select the treatments you want to give them. For example, if you're studying the effects of Valium on memory, you get to pick the doses of Valium that you give to people.

In a pseudoexperiment, however, you have little or no control over your subjects and independent variables. For example, suppose you're instead studying the effects of mild head injury on memory. You don't get to choose who has a head injury and who doesn't--you just have to take whoever comes.

Why do you care? Well, it's harder to draw conclusions from pseudoexperiments; in particular, it's generally difficult--even impossible--to make claims about causation. Let's say that in the example study above, you find that people with a history of head injuries do more poorly than control subjects in school. Now, maybe the head injury caused the poor school performance. Then again, maybe these head-injured people were generally dumber to begin with and had a tendency to do dumb things in every aspect of their lives. Then too, maybe these people weren't dumb; maybe they were ADHD types who can't sit still in school but who get thrills from participating in dangerous activities. It's hard to tell.

Okay, so given the problems with pseudoexperiments, why do them at all? Well, as I suggested above, sometimes they're the only way you can address an interesting question or problem. If you're comparing men to women, African-Americans to Caucasians people, children to adolescents, college students to elderly adults, or crack addicts to non-addicts, you don't get to pick who goes in what group--but it's still useful to know if there are differences between them, and careful experiments can help rule out possible causes of those differences.