A term coined by Terence McKenna to describe the dose of psilocybin mushrooms required to interface with the galactic entelechy and contact the Logos, in order to hear the plain-spoken voice of the Mushroom. To repeat, 5 dried grams of psilocybe cubensis ingested alone in a dark, quiet room should virtually guarantee an experience of the above and the often associated dissolution of the ego (ego death).

You may require less or more than this and your mileage may vary. See psilocybin mushrooms for a description of an experience like this.