E/N originally meant "Entertainment/News", it was used to describe general
catch-all sites that were designed around one specific person's taste. Everything/Nothing was a permutation of it describing the same type of site, because it covered
everything, but
nothing in particular. Famous E/N sites include
Stileproject, and
Something Awful (anyone know more obvious examples?)
You wouldn't necessarily call E2 an E/N site (unless you were trying to make a bad pun), because it's designed specifically to be a community. E/N sites are the dictate of one person or of a small group of people. The site revolves around this person/group's idea of what the ideal website would, in all circumstances, be. Lately, the term E/N has been applied to things like weblogs, or angsty online forum posts where people talk about their individual lives. In effect, E/N has come to mean content of personal interest to the author. In some cases, this content also interests a wide array of other people. In other cases, not.