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A solution commonly used during probe hybridizations that involve filters (such as Southern, Northern, or Western blots). The solution contains ficoll, bovine serum albumin, polyvinylpyrrolidone (PVP), and a high concentration of nonspecific DNA so the probe won't hybridize nonspecifically.

From the BioTech Dictionary at http://biotech.icmb.utexas.edu/. For further information see the BioTech homenode.

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