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Systemic mastocytosis is a rare autoimmune disorder which affects the whole body. It is caused by the invasion of a type of immune system cell (the mast cell) into tissues which it normally shouldn't go; this would produce autoimmune problems and symptoms such as inflammation. Mast cells, which are normally found in connective tissues, produce histamine.

From the BioTech Dictionary at http://biotech.icmb.utexas.edu/. For further information see the BioTech homenode.

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