Roger Rabbit's wife in the movie Who Framed Roger Rabbit?. Stays with Roger because he makes her laugh. Although married, she plays 'pattycake' with Marvin Acme from time to time (No, literally, pattycake).

This last fact was enough to lead the police to believe that Roger killed Marvin Acme. Jessica was willing to do anything to prove his innocence.

As a small side note, despite her last name, Jessica is not a rabbit. Apparently, Roger isn't called Roger Rabbit solely because he's a rabbit. Must be his last name.