The availability of MDMA and LSD on the street, along with most of the other "alphanumeric drugs" (e.g. 2C-B, 2C-T-7, 4-Acetoxy-DiPT, 5-MeO-DiPT, 5-MeO-DMT, pretty much everything mentioned in PiHKAL and TiHKAL) means one thing:

Chemistry graduate students gone bad.

These drugs are NOT easy to make. A synthesizer must have extensive experience in highly complex chemical reactions, laboratory procedure, etc.

So, basically, there are a lot of very, very smart chemistry students out there who have found a fun way to supplement their income. Or pay off their loans.